Composition:
Product name:
Prednisone Acetate Injection
Character:
This product is a suspension of fine particles. After standing, the fine particles sink and form a uniform milky white suspension after shaking.
Indications:
Prednisolone acetate injection is mainly used for allergic and autoimmune inflammatory diseases. It is widely used in active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, nephrotic syndrome, thrombocytopenic purpura, granulocytopenia, various adrenal cortical insufficiency, severe dermatitis, acute leukemia, etc., and is also used in the comprehensive treatment of some infections.
Adverse reactions:
There was no obvious adverse reaction in the application of physiological dose of glucocorticoid replacement therapy, and the adverse reaction mostly occurred in the application of pharmacological dose, and it was closely related to the course of treatment, dose, drug type, usage and route of administration. For example, systemic adverse reactions caused by intra-articular injection of this product are less and less severe, and the common adverse reactions are as follows:
1. Long-term use can cause the following side effects: Iatrogenic Cushing syndrome Features and posture, weight gain, lower limb edema, purple lines, bleeding tendency, poor wound healing, acne, menstrual disorders, avascular necrosis of the humerus or femoral head, osteoporosis and fractures (including vertebral compression fractures and pathological fractures of the long bone), myasthenia, muscular atrophy, hypokalemia syndrome, gastrointestinal irritations (nausea, vomiting), pancreatitis, digestion Ulcer or perforation, inhibited growth, glaucoma, cataracts, benign intracranial pressure syndrome, impaired glucose tolerance, and increased diabetes in children.
2. The patient may present with psychiatric symptoms: euphoria, agitation, delirium, restlessness, disorientation, and may also show inhibition. Psychiatric symptoms are prone to occur with chronic wasting diseases and people who have had mental disorders in the past.
3. Concurrent infection was the main adverse reaction of adrenal corticosteroids. It is mainly composed of fungi, tuberculosis bacteria, staphylococcus, Proteus, pseudomonas aeruginosa and various herpes viruses.
4. Glucocorticoid withdrawal syndrome. Sometimes patients with dizziness, fainting tendency, abdominal or back pain, low fever, loss of appetite, nausea, vomiting, muscle or joint pain, headache, fatigue, weakness after discontinuation of the drug can be considered as glucocorticoid dependence syndrome if they can rule out adrenocortical dysfunction and the recurrence of the original disease.
Pharmacology and toxicology:
This product is a corticosteroid drug. It has anti-inflammatory, anti-allergic and immunosuppressive pharmacological effects.
1. Anti-inflammatory effect: Glucocorticoids reduce and prevent the tissue's response to inflammation, thereby reducing the manifestations of inflammation.
2. Immunosuppressive effects: prevent or inhibit cell-mediated immune responses, delay allergic reactions, and reduce the expansion of the primary immune response.
3. Anti-toxic and anti-shock effects: glucocorticoid can fight against the stimulating response of bacterial endotoxin to the body, reduce cell damage, and play a role in protecting the body; It is also commonly used in the treatment of severe shock, especially toxic shock.
Storage:
Keep out of light and tightly sealed.
Veterinary Medicine GMP Certificate, Veterinary Medicine Production License
Quality Management System ISO9001, Environmental Management System ISO14001, Health Management System ISO45001
Model Unit of International Cooperation in Hebei Province
Top 30 Veterinary Medicine Enterprises in Hebei Province
Top 10 Veterinary Medicine Export Enterprises in Hebei Province
Are you a manufacturer? |
Yes, Shimu Group is a professional manufacturer established in 2001, located in Shijiazhuang high-tech industrial zone. Shimu Group is a comprehensive high-tech enterprise specialized in R&D, production, markering and technical service for veterinary drug and feed additive. |
Do you have GMP? |
Yes, the first GMP certification successfully got in 2005, and the latest GMP was updated in 2022. |
How does your factory control the quality? |
The company makes quality management as the focus of each work, and always implements the quality policy of "quality first, faithful and honest as the root". Quality Management Department consists of Quality Assurance Department (QA) and Quality Control Department-Central Laboratory (QC). The QC central laboratory is equipped with advanced inspection instruments and equipment that are compatible with the production scale. The existing quality inspectors all have years of experience in quality inspection of veterinary drug, and can independently judge and complete various inspection and monitoring work involved in the company's products, and have the ability to ensure that unqualified materials or intermediate products will not enter the next process. |
What certificates do you have? |
We have Manufacturing License and GMP. Also we have passed the certification of ISO9001, ISO 14001 and ISO45001. |
Can you provide registration? |
We have a professional registration team. We can provide registration documents for you. The documents include FSC, COPP, COA, Analysis Method, SMF, Stability Report, Instruction, and etc. |
Can we visit your company? |
Every year, many foreign customers come to visit our company. Welcome to visit our company.Shimu pharmaceutical co.,ltd which is veterinary medicine factory. |